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13-16 weeks : After assessment, your doctor will escalate the dosage to 8 mg once weekly for the next 4 weeks 17-21 weeks : If your body tolerates 8 mg for 4 weeks, your doctor will increase the dose to 12 mg once weekly onwards

The net: we need type II 5-alpha reductase to make DHT in our scalp skin

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A 2019 meta-analysis by Wei et al 11 reviewed the results of 4 RCTs on the use of onabotulinumtoxinA for TN and noted a significant improvement in reported pain values in comparison with placebo, with an estimated number needed to treat of 1.9 to achieve a 50% reduction in pain intensity

provide CAMS, a corpus of mental health posts (including Reddit) annotated by the authors for cause/effect categories