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If left unaddressed over the long term, renal vascular hypertension may potentially progress to HTN

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Discussion The results of the present study showed that serosal application of acetic acid to induce gastric ulcer has resulted in gastric damage with elevated levels of pro-inflammatory cytokines along with increased neutrophil infiltration, lipid peroxidation, cyclooxygenases and prostaglandins, in conjunction with depleted antioxidant GSH in the gastric tissue

NLRP3 inhibitor Oridonin can suppress the expression of IL-18 and IL-1, alleviate inflammation, preserve myocardial function and improve myocardial remodeling by reducing NLRP3 expression [89]

The detailed pharmacological therapeutic strategies are shown in Table 1