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Purified ferritin from glioblastoma-derived cell line has marked apoptosis-stimulating activity and are inhibited by neutralizing anti-ferritin antibody Ab rH02, however, isoferrin released from cultured neonatal astrocytes did not show this activity, suggesting that the transition of astrocytes to a malignant phenotype is accompanied by alterations in iron metabolic processes ( In recent years, an increasing number of studies have found that the inevitability of treatment resistance and recurrence in GBM may be due to the presence of cancer stem-like cells (CSCs) ( 2.2 Lipid metabolism 2.2.1 Lipid metabolism in ferroptosis In ferroptosis, the most essential process related to lipid metabolism is lipid peroxidation

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Pharmacogenomics 21(12):841851

This evaluation encompasses: Data on the strength and potency of the investigated drug

The researchers found that patients with intracranial hypertension (n=61) had significantly thicker peripapillary retinal nerve fiber layer and ganglion cell inner plexiform layer thickness with larger optic nerve head rim area than controls (n=65)