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Studies have shown that, on the one hand, Nrf2 promotes the expression of glutathione and GPX4 strengthens the function of the antioxidant system, and on the other hand, Nrf2 can also reduce intracellular iron accumulation by promoting the expression of ferritin and the simultaneous release of FPN1 storage and export

Regulation of TAM polarization TAMs mainly stem from monocytes originating in the bone marrow and are drawn to cancerous areas via the chemoattractant CCL2, which is produced by tumor cells [57]

The sLASER sequence employs slice-selective excitation, often using an asymmetric sinc pulse for improved slice profile, followed by two pairs of adiabatic inversions, such as hyperbolic secant pulses, in orthogonal directions to further define the chosen voxel, with far lower CSDE than if conventional pulses are used

whether these cell death modalities crosstalk to amplify injury or compensate for each other in the transition phase lacks systematic investigation

This complex mechanism of cytoskeletal organization dramatically enhances cellular mobility