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When the result of simultaneous use of paracetamol and flucloxacillin is included (1057 patients out of 53,000 hospitalizations), approximately 0.1% of all hospitalised patients have risk of having acidosis during the use of both drugs

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When present, side effects are typically mild and transient, potentially including slight drowsiness if administered too early (easily resolved by timing adjustment), mild headaches during initial adaptation in some individuals (usually resolving within days), temporary vivid dreams as sleep architecture normalizes, or rare reports of mild dizziness upon waking in sensitive individuals

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