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Non-parametric continuous variables were summarized as median and interquartile range (IQR), compared using the KruskalWallis test with Bonferroni-adjusted post hoc comparisons, and analyzed over time using the Friedman test followed by Wilcoxon signed-rank tests

The high sensitivity but lower specificity of the HepG2 cell model with hamster S9-mix therefore makes the model useful when a conservative approach to avoid false-negative results is the goal of the test strategy

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By replenishing glutathione, especially via IV, you can reduce oxidative damage and help mitochondria operate at their best

110 MiyagawaK.HayashiY.KuriharaS.MaedaA