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In the FY 2026 IPPS/LTCH PPS proposed rule, after considering the D.C

Decreased NAD + levels can impair the efficiency of the mitochondrial respiratory chain, resulting in reduced energy production, which may exacerbate obesity and related metabolic disorders (Amjad et al., 2021)

Geriatric use: Elderly patients may be more sensitive to NSAIDs, so it is recommended to use the lowest effective dose

doi: 10.1016/j.tips.2017.07.001 [DOI] [PubMed] [Google Scholar] 37

Ann Hematol 98:13331339 Coskun E, Keskin A, Suzer T et al (1998) Spinal cord compression secondary to extramedullary hematopoiesis in thalassemia intermedia