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Metformin treatment ameliorates diabetes-associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1

doi:10.1155/2020/9349063

Aging in females was characterized by a significant rise in IL-1, IL-4, IL-5, IL-6, IL-10, IL-12(p40), IL-12(p70), IL-17, CXCL-10, CXCL-1, MIP-1, MIP-2, and TNF, but several of these cytokines and chemokines were restored to a more youthful level with mAb treatment (Fig