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GHK-Cu and Angiogenesis Research Laboratory and in vivo studies found that GHK-Cu stimulates collagen synthesis, angiogenesis, and the modulated expression of glycosaminoglycans, proteoglycans, and metalloproteinases with in vivo animal models reinforcing these findings and reporting accelerated wound-healing rates and favourable wound-contracture properties

With injectable protocols, some patients report visible improvements in skin quality within 2-4 weeks

Larger jumps risk triggering intolerance that wouldn't occur with gradual progression

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Holzinger, B., & Mayer, L