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This mutation can affect the bodys ability to convert folic acid into its active form, leading to potential health issues

The RCT by Kuzminski et al

Isatuximab, carfilzomib, and dexamethasone in relapsed multiple myeloma (IKEMA): A multicentre, open-label, randomised phase 3 trial

however, I know there is a general reluctance to prescribe those in the UK

The lack of growth hormone receptor activation eliminates the concerning side effects associated with growth hormone therapy, and the peptides very short half-life prevents tissue accumulation