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CobaSorb test depends on the fact that newly absorbed B12 circulates in the plasma as holoTC

For intestinal diseases related to the gut-liver axis and liver diseases, oral administration is considered the most convenient method due to its simplicity and high patient compliance

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, , , ( , ), , 85 % 86 %, , 85.5 %, ( , ) 14 % 15 %, , 14.5 % ( , PlasACRYL) .In the oral formulations provided herein, enteric coatings, such as methacrylic acid copolymer coatings (e.g., Eudragit coatings), e.g

Integrating nanoencapsulated formulations into these platforms would allow encapsulation strategies to be optimized not only for average bioavailability, but for individual response patterns and co-morbidities