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MacLean, A

Pharmacological treatments Recent guidelines recommend the following classes of medications for the treatment of PDPN (Fig

McCoy et al., 2013)

Rare side effects can include allergic reactions, such as rash or itching

It does this by taking a methyl group from 5-methyltetrahydrofolate (the active form of folate), transferring it back to the cobalamin, and releasing free tetrahydrofolate