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Methods: In a prospective, multicentric cohort study in two large PC practices in Belgium between October 2020 and May 2023, a FibroScan measurement (for assessment of steatosis by CAP and of LSM as a surrogate for fibrosis) and clinical examination (waist circumference (WC) and BMI) was performed at baseline and follow-up

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Among them, the fat sensory nerve will convey the metabolic signal in AT to the central nervous system, and then instruct AT through the sympathetic nerve (8486), so that it can carry out the corresponding lipolysis and thermogenesis according to the instruction (87, 88) ( Figure 2 )