glutathione peroxidase family The family: Discoveries and mechanism Genome-wide analysis of Glutathione peroxidase

HEK 293T cells were lysed (50 mM Tris pH 8.0, 150 mM NaCl, 5 mM MgCl 2 , 0.5 mM EDTA, 0.5% NP-40, 10% glycerol, 1 mM TCEP, protease and phosphatase inhibitors) and the lysate was clarified by centrifugation, then diluted to 10 mg/mL

Journal of Biological Chemistry, 289 (25), 1791717931

Lipid peroxidation and oxidative damage induced by ROS can result in cellular damage and death, which aligns with the hallmarks of ferroptosis

Iron Nitroprusside (FeNP) is an iron-based self-therapeutic nanomaterial that exerts significant anti-tumor effects in OC by inducing ferroptosis and chemodynamic therapy (CDT)

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