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4 Discussion Current management of schizophrenia includes administration of antipsychotics, which are well known for increasing the risk of metabolic syndrome

Brain infarct volume was quantified at 21 days post-MCAO

10.1038/s41598-023-33403-9 65 KongY.LiuS.WangS.XuJ.HuY.JiangS.et al (2023b)

Moreover, senescent cells do not divide and accumulate slowly

Average CNV lesions per eye were for 6weekold VEGFA hyper mice 18.41, for VEGFA hyper /Il1r1 / mice 8.79, for VEGFA hyper /Nlrp3 / mice 6.26, but for VEGFA hyper /Casp1 / /Casp11 / mice only 2.71 ( P value compared to VEGFA hyper mice of 0.0002)