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It's funded by the cosmetics industry trade association, but the Expert Panel itself, independent dermatologists, toxicologists, pharmacologists, and other scientists nominated by consumer groups, government, and industry alike, operates separately from that funding, in fully open public meetings with formal comment periods

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The Neh2 domain is a regulatory domain containing the DLG and ETGE binding motifs, through which NRF2 interacts with its major negative regulator, KEAP1, and is essential for the KEAP1-mediated degradation of the protein by the proteasome [128, 143,144,145]

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