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doi: 10.4103/0973-029X.140762 197 ParaskevopoulouMDHatzigeorgiouAG

Vande Casteele N, Khanna R, Levesque BG, Stitt L, Zou GY, Singh S, et al

Environmental stress can induce immediate responses through transcriptional changes, enabling cells to adapt to and survive external insults (Chen et al, 2008, 2003

The company completed a Phase IIb study in obese subjects, but the trial failed to show statistically significant weight loss versus placebo at its primary endpoint