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A 2.4 gram dose delivered five clinical benefits in studies, including a 54% increase in recovery and a reduction in lean muscle loss during calorie deficits, and up to 144% better strength recovery and 47% reduction in muscle fatigue versus placebo

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Factors such as cost savings, convenience, absorption issues, potential digestion, and comfort with self-administering injections can affect patients preferences

Once training began, both groups gained about 2 kilograms (4.4 pounds) of lean body mass over 12 weeks, but creatine users did not gain more than those who did not take it, indicating the supplement gave an early bump in lean body mass but did not enhance long-term gains from resistance training

While we continue to believe that Medicare CQMs are a valuable transition step on our building-block approach for Shared Savings Program ACOs' progress to adopt digital quality measurement, under the policies we are finalizing in this section of this final rule, Shared Savings Program ACOs would continue to have the option to report the APP Plus quality measures using the MIPS CQM collection type for performance years 2025 and 2026