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Phenotypic heterogeneity of type 2 diabetes and risks of all-cause and cause-specific mortality

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During lysis samples were sonicated three times for 1 s (amplitude 0.30) using a 5/64 probe (QSonica Q55A), cleared by centrifugation (10,000 g at 4 C for 10 min) and protein concentration was equalized between samples

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Overall, the comparative analysis highlighted distinct differences among the constituents, particularly in GI absorption, BBB permeation, and CYP inhibition potential given in Table 2, which may influence their biological activity and suitability as therapeutic candidates