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(2021) 13:e19343

Key Ingredients: High-Dose Vitamin C : Promotes collagen synthesis, protects skin from oxidative stress

In 1989 he moved to the University of California, San Diego, where he is an investigator of the Howard Hughes Medical Institute and professor in the department of pharmacology and of chemistry and biochemistry

doi: 10.1186/s13046-020-01641-8 31 LegendreCGarcionE

Notably, Musicki and colleagues demonstrated that O-GlcNAcylation of eNOS at Ser-1177 prevents its activation by shear stress and VEGF signaling, highlighting a direct mechanistic link between PTM dysregulation and penile vascular dysfunction[54]