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Chronic oxidative stress, mitochondrial dysfunction, Nrf2 activation and inflammation in the hippocampus accompany heightened systemic inflammation and oxidative stress in an animal model of Gulf War illness

Graphical Abstract Plain Language Summary Major depressive disorder (MDD) is a common disease defined by sadness and a loss of interest or pleasure in activities

Glutamine, the most abundant amino acid in the body, is an important component of tumor metabolic reprogramming as it participates in metabolizing nonessential amino acids, thereby providing energy for tumor development [101]

The cytoplasmic ADNP is also known to interact with cytoskeletal microtubules (MTs) and MT-associated proteins, including Tau and MT end-binding proteins (EB1 and EB3), related to ASD pathology [293]

The levels of liver function indicators (ALT, AST, and ALP) and kidney function indicators (BUN and CREA) were maintained in the normal range (Supplementary Fig