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In acute wounds, the clot is further degraded via the activation of the serine protease urokinase plasminogen activator [92]

Emerging evidence suggests that Cu(II)-resveratrol systems may overcome conventional chemotherapy resistance through parallel induction of paraptosis and cuproptosiscell death pathways less prone to oncogenic mutation-based evasion

In the case of dietary ferric iron, the ferric reductase Dcytb which is related to cytochrome bpresumably reduces Fe 3+ to Fe 2+ at the extracellular surface of the apical membrane before uptake through DMT1