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This suggested a dual action on the peripheral and central nervous system

Clinical Nutrition

Collectively, these studies suggest MPs/NPs potentially exhibiting neurotoxic effects on cerebral tissue and vascular integrity, while negative effects during fetal exposure may be mitigated by placental adaptation

10.1016/j.molmet.2018.09.008 22

Then, proteomic analysis identified nine enriched proteins in LP-EVs directly associated with acne improvement, including mucus-binding protein, cell wall hydrolase, lipase, and thioredoxin