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elegans , high proteostress that likely overwhelms chaperone, proteasome, and autophagy functions can trigger the production of large (~3.8 m) vesicles called exophers that concentrate, and somewhat selectively remove, aggregated proteins such as transgenically expressed Huntingtin polyQ expansion proteins 6,7,8

Psychiatry 83 , 6169 (2018)

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Psychiatry 87 YaoJ