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Discussion HMOX catalyses intracellular haem degradation, producing biliverdin, iron and CO

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Therefore, targeting TFEB may be a promising strategy for the treatment of AD

We supposed that Nrf2-mediated biosynthesis of GSH is impaired by the stimulation of CS, whereas GHK-Cu modulates Nrf2, attenuates pulmonary oxidative stress and thereby restores GSH depleted by CS

OTU absolute abundance table and mapping file were used for statistical analyses and data visualization in the R statistical programming environment package phyloseq 58 or web-based tool MicrobiomeAnalyst 52