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In vitro studies demonstrated that glutamine supplementation decreased the production of pro-inflammatory cytokines IL-6, IL-8, and/or TNF, while increasing the production of anti-inflammatory/regulatory cytokine IL-10 in various activated adult human immune cells, including intra-epithelial lymphocytes (IELs), intestinal mast cells, peripheral mononuclear cells (PBMCs) and monocytes (162165)

[DOI] [PubMed] [Google Scholar] 41.Dixon R.V., Skaria E., Lau W.M., Manning P., Birch-Machin M.A., Moghimi S.M., et al

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While the effects are often reversible upon drug discontinuation, repeated exposure increases the likelihood of persistent damage (Lai et al

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