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Our quantitative RT-PCR results also show that female CBA/CaJ mice have elevated levels of Nrf2 that promotes the transcriptional induction of a number of Phase II detoxification genes, including Gsta , Gstm , and Gstp

On tolerability, both compounds produced mild-to-moderate gastrointestinal adverse events (nausea, diarrhea, constipation, vomiting), typically during dose escalation

Thus, VEGF and IL-6 may contribute to the development and progression of vasogenic ME in BRVO

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