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Together, these findings indicate that while strong oxidants, such as H 2 O 2 , favor irreversible thiol overoxidation and suppress disulfide chemistry, reactive nitrogen species provide a physiologically relevant pathway for disulphide cross-linking of TTR

M., Hsu J., Ferguson M., et al., A Brain Network for Deep Brain Stimulation Induced Cognitive Decline in Parkinson's Disease, Brain 145, no

Intestinal macrophages from individual with Crohns disease have reduced selenoprotein expression Utilizing published scRNAseq data from inflamed and non-inflamed colonic biopsies from individuals with CD and control biopsies from 71 donors, changes in macrophage populations and gene expression were assessed

Chiu ST, Hsieh FJ, Chen SW, Chen CL, Shu HF, Li H

Proposed mechanisms for the role of iron in neurodegeneration include increased oxidative stress, possibly due to enhanced generation of reactive oxygen species (ROS) associated with increased protein aggregation [26, 117]