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The etiology of PD remains a topic of debate, as it has been shown that both genetic factors, such as mutations in SNCA (Polymeropoulos et al., 1997) and Parkin (Kitada et al., 1998), and environmental exposure, such as the pesticides paraquat and maneb (Cicchetti et al., 2005), may cause the disease (Kouli et al., 2018)