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Treatment with rFGF4 inhibits ferroptosis in liver cells by increasing CISD3 levels and activating the Nrf2/HO-1 signaling pathway [251]

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Overall, while traditional EV detection methods have contributed to our understanding of EV biology, their limitations underscore the need for more advanced, sensitive, and standardized techniques to fully exploit the potential of EVs in biomedical research and clinical applications

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