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According to some researchers, inflammation along with histamine release causes brain fog in people with mast cell activation disorders

However, in aging, it is very common to find cases of incipient atherosclerosis, which leads to a reduction in blood flow and cerebral oxygen consumption (Bakker et al., 2014)

doi: 10.3390/ijms232113077 MoralSanz, Javier, FernandezRojo, Manuel A., Colmenarejo, Gonzalo, Kurdyukov, Sergey, Brust, Andreas, Ragnarsson, Lotten, Andersson, sa, Vila, Sabela F., CabezasSainz, Pablo, Wilhelm, Patrick, VelaSebastian, Ana, FernndezCarrasco, Isabel, Chin, Yanni K