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Description

10.1002/dvdy.22308 36 GambaL.CubedoN.LutfallaG.GhysenA.Dambly-ChaudiereC

Nature Reviews Endocrinology , 17(7), 391-405

CONCENTRATION AND SOLUBILITY-

doi: 10.7759/cureus.40948 42 JonesRMMercanteJWNeishAS

According to the A-tau interaction hypothesis, A and tau pathology, which results in synaptic dysfunction, neuronal death, and cognitive impairment (96), is determined by the intrinsic interaction with A and tau (A42 enhances tau phosphorylation, truncation, and aggregation, while tau can increase A synthesis)