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Boosting recombinant inclusion body production-from classical fed-batch approach to continuous cultivation

doi: 10.3390/life12122101 Summary Keywords interstitial lung disease, systemic sclerosis, cyclophosphamide, rituximab, mycophenolate mofetil, tocilizumab, nintedanib, pirfenidone Citation Kamenova A, Tzouvelekis A and Margaritopoulos GA (2023) Recent advances in the treatment of systemic sclerosis associated interstitial lung disease

Briefly, mice exhibiting the FUSALS phenotype (characterized by FUS translocation from the nucleus to the cytoplasm) demonstrated longer lifespan, reduced disease severity and improved histological patterns when intracellular HSPA1A was overexpressed (Piavchenko et al., 2024