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FDA statement Semaglutide receptor-engagement model - PeptideFox semaglutide explainer, Chapter 6

Try to switch up the spot where you get the injection each time to avoid irritation

Clean the skin with soap and water (do not need to use an alcohol swab) and pat dry

In vivo models commonly used in this research include collagen-induced arthritis (CIA) in rodents, monosodium iodoacetate (MIA) cartilage injury models, and surgical destabilization of the medial meniscus (DMM) models for osteoarthritis