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Nature 590 , 480485 (2021)

[68] [45] Ligands [edit] Agonists [edit] Mixed [edit] Antagonists [edit] Steroidal antiandrogens (e.g., cyproterone acetate, chlormadinone acetate, spironolactone, oxendolone) Nonsteroidal antiandrogens (e.g., flutamide, nilutamide, bicalutamide, enzalutamide, apalutamide, RU-58841) N-Terminal domain antiandrogens (e.g., bisphenol A, EPI-001, ralaniten, JN compounds) [70] As a drug target [edit] The AR is an important therapeutic target in prostate cancer