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However, their effectiveness depends on dosage, bioavailability, and individual health status, necessitating careful, evidence based application

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The knockdown also changes correlations of the levels of OGDHC, GDH and GOT2 with those of the malate and isocitrate dehydrogenases

More recently a group of secondary metabolites known as xanthones have been isolated from the pericarp of the mangosteen Garcinia mangostana and are attributed the medicinal and health beneficial properties of the fruit (15)

64,66 This metabolic disorder not only affects the energy supply of oocytes but also alters the balance of intracellular metabolic products, affecting cellular signaling and gene expression, ultimately leading to abnormal follicular development and a decline in oocyte quality