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Stem Cells 33(7):23062319

Succination of Keap1 and activation of Nrf2-dependent antioxidant pathways in FH-deficient papillary renal cell carcinoma type 2

These mutations lead to constitutive activation of Ras, resulting in persistent activation of the MAPK pathway, promoting uncontrolled cell proliferation and survival

Martin and Delarasse, 2018)

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