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TB4 has various therapeutic uses, from surgery and soft tissue injury repair, Traumatic Brain Injury, to reversal of neurotoxicity and deleterious effects of heart attack

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Such biomarkers include zonulin, fatty acid binding proteins (FABP), citrulline, glucagon-like peptide (GLP)-2, LPS, LPS-binding protein (LBP) or fecal 1 antitrypsin (AAT), for example