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Defects in the synthesis of heme (i.e., iron + protoporphyrin) Iron deficiency, ACD, sideroblastic anemias 3

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Alternative approaches involve engineering CAR-T cells to secrete anti-PD-L1 antibodies or utilizing knockout technologies (CRISPR/Cas9) to eliminate inhibitory molecules (PD-1, CTLA-4, LAG-3) within the CAR-T cells themselves (9296)