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A.HasturkH.LiuJ.et al (2020)

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While DBS can alleviate clinical symptoms in AD patients and slow down brain atrophy, its invasiveness limits patient acceptance, and the acceptance rate for DBS among patients is generally low

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Cells, 11 (18), Article 2771

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This implies that the downregulation of FOXO3a protein may contribute to resistance to cetuximab

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