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HPA, Hypothalamic-Pituitary-Adrenal

In a pro-survival context, caspase-8 can cleave RIPK1 thereby limiting apoptotic and necroptotic cell death [62]

MaR1 also activates the orphan nuclear receptor ROR, promoting an anti-inflammatory macrophage phenotype [34]

In addition to their role in detoxification, bacterial GSTs are also involved in other metabolic processes like the degradation of lignin (Allocati et al., GSTs in Plant-virus Interactions Plant viruses are obligate biotrophic pathogens that need living tissues for their multiplication