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The experimental data of rats show that type I fibres produced less force than type II fibres ( Therefore, in summary, although positive adaptive changes in diaphragm structure could be found in patients with COPD, negative structural changes still dominate (Levine et al., 2013)

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Chem Rev (2018) 118:174269

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Although some deaths have apparent associations with treatment-related AEs (e.g., TMA), the etiology is not always clear