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(26) Iron: Necessary for immune cell proliferation and maturation, particularly lymphocytes, which are integral to the immune response

Environ Health Perspect 118:14711475

Phosphoinositide-3-kinase The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) is an intracellular pathway involved in the regulation of a variety of critical cellular physiological processes involved in the cell cycle growth and proliferation and apoptosis, protein synthesis, and drug resistance in response to stimulation by growth factors, cytokines and hormones (Leslie and Downes 2002)