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Pain 154 , 26162625 (2013)

Although it is yet unknown whether breakage is mechanical, enzymatic or ROS-induced it is however admitted that the most common sperm DNA alteration is oxidative damage leading to the formation of oxidized bases such as the 8-OHdG (8-hydroxy-2-deoxyguanosine) residue

SNAP-8 supports a smoother appearance by helping reduce the intensity of those contraction signals, which can lessen the depth of visible creasing over time

The human body is equipped with enzymes, specifically peptidases, that are ruthlessly efficient at breaking down small peptides

Moreover, as shown in the present study, the GSH levels do not necessarily decrease in parallel with ROS production because of its compensatory mechanism