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The relationship between excitotoxicity and ALS can be exemplified by the finding that the cerebrospinal fluid of patients with the disease had three-fold higher concentrations of glutamate, aspartate, N -acetyl-aspartyl glutamate, and N -acetyl aspartate when compared to healthy controls [199]

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The condition is increasingly recognized as complex, influenced by genetic, neurobiological, and environmental factors, highlighting the limitations of relying solely on behavioral criteria

Semaglutide is the active ingredient in Ozempic, and it could be used in a generic version once available in the future

FDA Alert (2022): FDA alerts health care professionals of risks to patients exposed to xylazine in illicit drugs