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Description

Iron homeostasis imbalance and ferroptosis in brain diseases

In a PD mouse model induced by intraperitoneal injection of salsolinol (SAL), and in SAL-treated SH-SY5Y cells, GSH expression was significantly reduced, whereas levels of ROS, Fe 2+ , ACSL4, MDA, 4-HNE, and -Syn were markedly elevated

Platinum (II) class antitumor drugs such as cisplatin and oxaliplatin, widely used in cancer chemotherapy, target DNA damage and overall cytotoxicity in tumor cells, resulting in cell death (135)

PMID: 39482401 Sci Rep A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase

NAC and glutathione share several important benefits, which is why they are often discussed together, particularly when it comes to longevity supplements