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There is no evidence to suggest that consuming alcohol before getting a COVID vaccine impacts the vaccines effectiveness, though some experts recommend avoiding alcohol 24 hours before vaccination

Journal of Applied Physiology, 104(5), 1366-1373

The best sources of B12 are found in organic meat and eggs

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The investigators reported that oral AOD-9604 administration in rodent models produced measurable increases in fat oxidation and reductions in body fat, and that direct application of the compound to ex vivo human adipose tissue produced concentration-dependent increases in lipolysis [2]