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Its high copy number and lack of histone protection make it more vulnerable to endogenous attack by reactive oxygen species (ROS)

Science 319 , 16681672 (2008)

Start with a low dose to assess the impact and any adverse events

The FeSOD-2 of is a mitochondrial SOD with an elongated N-terminal protein extension, reminiscent of a bipartite apicoplast-localized protein [43, 86]