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(69) reviewed DBS and lesioning techniques for PD, addressing indications, selection processes, and management strategies

The common adverse effects include mild, transient headaches, and skin eruptions ranging from mild to severe drug reactions such as fatal StevensJohnson syndrome and toxic epidermal necrolysis, kidney and liver dysfunction, thyroid dysfunction, severe abdominal pain, and fatal complications such as air embolism or sepsis due to incorrect method of IV administration.[] TOPICAL FORMULATIONS Topical formulations of glutathione are also available in the form of cream, facewash, soap, and lotion

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This is why experts often recommend monitored use rather than continuous, self-prescribed intake

doi:10.1016/S0891-5849(99)00177-X