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doi:10.3389/fncel.2020.00164

Besonders bei chronischen Schmerzzustnden zeigt sich eine doppelte Wirkung : sowohl eine direkte Schmerzreduktion als auch eine indirekte Verbesserung durch optimierten Schlaf

Moreover, bypassing the bloodbrain barrier altogether by direct intrathecal administration of the B cell-depleting agent rituximab was also ineffective in progressive MS (Komori et al., 2016